Pharmaceutical excipients are an important part of pharmaceutical preparations, and their role is to ensure that drugs are selectively transported to tissue sites in a certain way and procedure so that drugs are released in the body at a certain speed and time. Therefore, the selection of appropriate excipients is one of the key factors for the efficacy of pharmaceutical preparations. Pharmaceutical excipients Hypromellose (HPMC) is one of the most widely used pharmaceutical excipients at home and abroad. HPMC can be used as a film-forming agent, adhesive, sustained-release agent, suspending agent, disintegrating agent, etc. It is often used to make coatings for empty HPMC capsules.

    HPMC has many properties that other excipients do not have. It has excellent water solubility in cold water, as long as it is added to cold water, it can be dissolved into a transparent solution with a little stirring. Second, it is a non-ionic cellulose ether, and its solution has no ionic charge and does not interact with metal salts or ionic organic compounds, thus ensuring that HPMC does not react with other raw materials during the production process. In addition, this material has strong anti-allergy, and with the increase of the degree of substitution in the molecular structure, the anti-allergy also increases. Compared with the medicines using other traditional excipients, the quality of medicines using HPMC as excipients is more stable during the validity period.

    HPMC is metabolically inert. As a pharmaceutical excipient, it is not metabolized or absorbed, so it does not provide heat in medicines and foods. It has unique applicability to low-calorie, salt-free, non-mutagenic medicines and foods for diabetics.

    HPMC is also relatively stable to acid and alkali, but if it exceeds pH 2~11 and is subjected to a higher temperature or longer storage time at the same time, the viscosity will decrease. Aqueous solutions can provide surface activity, showing moderate surface tension and interfacial tension values. It has an effective emulsifying effect in a two-phase system and can be used as an effective stabilizer and protective colloid. The aqueous solution has excellent film-forming properties and is a good coating material for tablets and pills. The film formed by it is colorless and tough. If you add Gan Oil can also increase its plasticity.